Abstract: Cu-Zn-Al-Mn, Cu-Zn-Al-Ce and Cu-Zn-Al catalysts were prepared by coprecipitation method. Their activities were evaluated using a feed gas composed of H2(66%),CO(27%),CO2(3%) and N2(4%). The results indicated that Mn was an effective promoter to improve the activity and thermal stability of Cu-Zn-Al catalyst. The study of catalyst characterization using XRD (X-ray Diffraction) and SEM (Scanning Electron Microscopy) also showed that Mn promoter was favorable for the dispersion of CuO. The activity of Cu-Zn-Al-Mn catalyst was further evaluated using a CO2-rich feed gas composed of H2(50%),CO(25%),CO2(20%) and N2(5%). The results indicated that both STY (space time yield) and selectivity of methanol were decreased when CO2-rich syngas was used. Under tested ranges, the STY was decreased 11%～25% and the selectivity was 93% to 95%, decreasing in the range of 3.5%～5.7%.