Abstract: The experiment of hydrogen production from sorption enhanced steam methane reforming (SE-SMR) were done in a laboratoryscale fixedbed reactor system, and the effects of temperature, CH4 flow rate, particle size and different sorbents on the reaction processes of SE-SMR were investigated. The results indicate that the optimal reaction temperature for SE -SMR was affected by the reaction thermodynamic and kinetics. With CaO as sorbent, the optimal reaction temperature is in the range of 600 ℃～700 ℃ at atmosphere pressure. The flow rate of CH4 should be determined based on the sorbent amount in reactor and the required time for sorption enhanced period. The particle size should be larger than 90 μm and pure CaO and new Cabased CO2 sorbentCaO/Ca12Al14O33 both achieve good sorption enhanced effects.