Abstract: The cordierite honeycomb ceramics (CC) was coated with Mn, Cu, Ce modified TiO₂, and W modified V₂O₅ in sequence by coating method. A series of monolith catalysts were evaluated at 120～550 ℃ for the selective catalytic reduction (SCR) of NO by urea. Compared to commercial catalyst V₂O₅-WO₃/TiO₂, the SCR performance was significantly improved between a wide temperature with the introduction of Mn, Cu, Ce. The results of characterization suggested that the activity improvement may be contributed to the suitable acidity and basicity of catalyst surface, the high ratio of V⁴⁺/V⁵⁺, the existence of anatase phase TiO₂ and the good redox capability of complex catalyst. This study provides a potential catalyst system for the removal of NO_x from diesel engines.