Abstract: ZSM-5@Beta core-shell molecular sieve was prepared by dynamic hydrothermal synthesis method using ZSM-5 adhered Beta seed crystals as the core phase, and polydiallyl dimethyl ammonium chloride (PDDA) was used as a coupling agent to adhere Beta seed crystals on the surface of ZSM-5. The structure and physical properties of composite molecular sieves were characterized by XRD, N₂ adsorption-desorption, SEM, TEM, ICP, NH₃-TPD and Py-FTIR. The catalytic performance of composite molecular sieves for alkylation of 2-methylnaphthalene (2-MN) with methanol was investigated. The results showed that ZSM-5@Beta composite molecular sieve prepared by this method had a core-shell structure, and the particle size was about 500 nm. Compared with mechanically mixed binary molecular sieve, core-shell molecular sieve had higher specific surface area and external surface area, lower acid strength and stronger acid center density. Through the construction of core-shell interface and hierarchical porous, the catalytic activity was improved by shell phase Beta molecular sieve with 12-membered ring channel, and the catalytic selectivity was improved by core phase ZSM-5 molecular sieve with 10-membered ring channel in the alkylation reaction of 2-MN with methanol. The 2,6-/2,7-DMN ratio in the products reached 1.35, and the yield of 2,6-DMN reached 4.29%.