Abstract:  Two-bubble class model for Fischer-Tropsch synthesis in slurry bubble column has been developed. Three models including two-bubble class model, perfected mixed model and multi-stage series model have been contrasted for Fischer-Tropsch synthesis. The perfected mixed model is the most appropriate in simulation of kinetics for Fischer-Tropsch synthesis. The multi-stage series model can approximately simulate reaction results of Fischer-Tropsch synthesis in slurry bubble column when the series number is appropriate, and it can be used in simulation of the effects of back mixing on reaction behaviors. The two-bubble class model is the best selection to describe the relations between the hydrodynamics and the reactions in slurry bubble column for Fischer-Tropsch synthesis.