Abstract: WO₃-TiO₂/SBA-15 catalyst was prepared by inner-pore hydrolysis method; it was characterized by XRD, SEM, EDS, N₂ sorption, FT-IR, TG-DTA and UV-vis and used in the photocatalytic oxidative desulfurization of diesel oil. The effects of WO₃ and TiO₂ loading and calcination temperature and time on the performance of the WO₃-TiO₂/SBA-15 catalyst in its photocatalytic oxidative desulfurization were investigated. The results indicated that the optimum loadings of WO₃ and TiO₂ were 1.6% and 15%, respectively, and corresponding calcination temperature and time were 500℃ and 3h, respectively. Over the WO₃-TiO₂/SBA-15 catalyst prepared under the optimum conditions, in which the hexagonal mesoporous structure was well retained, the desulfurization rate of model diesel oil reached 87.9%. Moreover, the WO₃-TiO₂/SBA-15 catalyst also exhibited excellent reusability after regeneration.